The nonequilibrium molecular dynamics simulation was conducted in order to clarify the effects of the surface adherent structures in nanometer scale on a thermal resistance at a liquid-solid interface as well as the reduction mechanism. The surface structural clearances and the potential parameter between liquid molecules and solid atoms were changed as the calculation parameters in order to discuss general nanostructural effects on the interfacial thermal resistance. The local nonequilibrium behaviors were observed between the nanostructures depending on the degrees of freedom of the liquid molecules and the diffusion coefficients of liquid molecules at the interface are enhanced by the local nonequilibrium state depending on the surface adherent structures in nanometer scale only in the case of Lennard-Jones potential liquid model.