Host: The Japan Society of Mechanical Engineers
Name : [in Japanese]
Date : October 30, 2018 - November 01, 2018
This paper reports a method for fixed-point observation of a fat fiber with mature adipocytes. The fat fiber consisted of a core consisting white fat cells suspended in collagen and a shell consisting of alginate gel. We showed that the average size of lipid droplets in the fat fiber was about 3 times larger than the 2D culture. By tangling the fat fiber with pillars, we succeeded in observation of the time-dependent change in the size of lipid droplets at a specific area of the fat fiber. Owing to fixed-point observation of mature adipocytes, we believe that our method will be useful for the study of lipid metabolism.