Host: The Japan Society of Mechanical Engineers
Name : [in Japanese]
Date : October 30, 2018 - November 01, 2018
Electrical stimulation has been known as one of the ways to mature cells and tissues. Here we present an electrical stimulation device for fiber-shaped 3D tissues to be matured. We fabricated cell-encapsulating hydrogel microfibers (cell fibers) using a double coaxial laminar flow microfluidic device and succeeded in controlling the diameter of the core of the fabricated cell fiber. In addition, we succeeded in fixing the cell fiber on a dish by adhesive hydrogel and confirmed that the fixed cell fiber can stably be set in the electrical stimulation device for more than 2 weeks. We believe that our approach would be effective to mature fiber-shaped 3D tissues in vitro.