複数センサ情報を用いたマイクロハンドシステムによる微小物体の自動剛性計測

抄録

Recently, with the development of life sciences, measurement of cell characteristics has been carried out to evaluate life phenomenon. The cell stiffness is one example of these characteristics and has much attentions. It is known that cell stiffness changes depending on the status of the cell. Thus, stiffness measurement is one of the important parameters to evaluate a cell. However, since measuring cell stiffness requires nano order manipulation and sensing, cell stiffness has not been extensively researched. Furthermore, it requires accurate operation skills and is difficult for humans. In this paper, we propose an automated stiffness measurement system. This system is combining force data and image data, and a multi-scale simultaneous observation. multi-scale simultaneous observation is realized with fusion of two different enlargement magnifications microscopes. By using this system, an automated and high-precision cell stiffness measurement is achieved.