We report a case of mandibular and maxillary fractures with SULBACILLINⓇ-induced pneumonitis. A man in his sixties fractured the maxilla and mandible in a fall, and was admitted for occlusal deviation. SBT/ABPC was administered to prevent infection, but SpO2 decreased and shadows were found bilaterally in the lungs on chest radiographs. Because DLST was positive, drug pneumonia due to SBT/ABPC was diagnosed. Due to the fracture, early surgery was considered necessary. An operation under general anesthesia was judged to be impossible due to poor ventilation caused by the drug pneumonia. After local anesthesia, only intermaxillary fusion surgery was performed, and after the pneumonia had improved, open reduction and internal fixation were performed under general anesthesia. About 3 years after the operation, there is only a slight deviation on the right side upon opening, and the maximum opening amount is 38 mm. The patient shows no signs of recurrence.