日本口腔インプラント学会誌
Online ISSN : 2187-9117
Print ISSN : 0914-6695
ISSN-L : 0914-6695
原著
銀無機系抗菌剤のYDAフィラーを含むテンポラリーセメントの抗菌性
作 誠太郎山本 宏治
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ジャーナル フリー

2003 年 16 巻 1 号 p. 11-17

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YDA filler (a silver ion inorganic system antibacterial agent) has been shown to stabilize antimicrobial activity when added to dental resin. Due to this property, this study examined the application of YDA filler to temporary cements and its effects on bacteria.
The sample materials used were zinc oxide eugenol cements and impression paste with YDA filler. Streptococcus mutans, and Actinomyces viscosus were used as the test bacteria. Anaerobic culturing was done for 10-12 hours, at 37℃ after the trial bacteria had taken in 5 ml TSBY including 0.5% yeast extract. Afterwards, they were adjusted using RTF at 1×106 RTF/ml. Next, the trial cement pieces were immersed in adjustment bacterial liquid, with anaerobic culturing for 12 hours, at 37℃. Bacterial quantities, after 10 X serial dilution, were measured using RTF. Each dilution liquid (0.1ml) was dropped in the TSBY plane culture medium with 4 days of anaerobic culturing at 37℃. Culture media with 100 colonies were chosen and the number of bacteria counted. The cement pieces were soaked in 10 ml RTF for 12 hours to measure the Ag ion concentration that dissolved from the cement, using inductive coupling plasma emission analysis. Other examinations researched:the physical properties, surface quality, and Ag ion uptake in bovine dentin.
0.1-30.0%wt YDA-filled impression paste had no bacteriocidal effects on all test bacteria. However, 5.0%wt YDA-filled zinc oxide eugenol (ZOE) cement showed bacteriocidal effects on all trial bacteria. For leachability, there was Ag elution from 5.0% or 30.0% wt YDA-filled ZOE cement. For physical properties, YDA-filled ZOE cement had similar results to the control high-bond cement. However, YDA-filled ZOE cement displayed adhesion for titanium different from that of the control cement. Using SEM and EPMA, Ag ion was not observed on the cement surface. Also, there was no Ag+ uptake in bovine dentin.
YDA-filled temporary cements have bacteriocidal properties and so have the potential to be used as a temporary adhesive for prosthetic dental implants, because of its characteristics of bonding with titanium.

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© 2003 公益社団法人日本口腔インプラント学会
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