超薄層HAコーティングインプラントに関する実験的研究

―第2報　骨接触率による純チタンインプラントとの比較―

抄録

Hydroxyapatite (HA) coated implant is clinically significant and some kinds of these implants are now being used in the clinical scene.
We already examined an ultra-thin HA coated implant using the thermal decomposition method in a pathological study, and acquired good results. In the second study, we embedded implants of ultra-thin HA layered type (HA-type) and pure titanium type (Ti-type) in the femur of rabbits, and compared the bone contact ratio surrounding the implants.
1. Measurements of the thickness of the bone for every point of the HA-type and Ti-type in both groups showed an upward tendency with time within the same type. In a comparison of the same point of the HA-type and Ti-type, the direction of the HA-type showed a higher value than the Ti-type in many cases.
2. When the bone contact ratio at each point was compared, in all weeks the direction of the HA-type showed a higher value than the Ti-type. Moreover, a significant difference was found among both at 2, 4, and 8 weeks. However, no significant difference was found at 12 and 24 weeks.
As the ultra-thin HA coated implant using the thermal decomposition method could bond with a new bone at an early stage, and could achieve initial fixation quickly, we consider that it is useful in clinical settings.