This review aimed to verify the effects of nutritional and dietary interventions in the prevention of long-term frailty. We collected the epidemiological knowledges of nutrition and diet for malnutrition, locomotive syndromes, sarcopenia, and frailty. However, there is a lack of dietary intervention studies on frail elderly, especially in the realm of quality clinical trials. Therefore, we summarized the reasons why it is difficult to obtain the effective results by dietary interventions and took up some effective practice cases. In the context of the prevention of long-term frailty, there are complexed factors leading to malnutrition, locomotive syndromes, sarcopenia, and frailty. According to the risks and individuality of older adults, flexible interventions are needed, and it is desirable to verify the medium- or long-term effects of interventions.