光造形法によるハイドロキシアパタイト製傾斜気孔人工骨の作製

抄録

  Graded porous scaffolds were fabricated via stereolithography. For the geometrical design, an inverse body-centered-cubic structure and four-coordinate lattices graded structures were considered. In the manufacturing process, a photosensitive resin containing hydroxyapatite particle was spread on a substrate and scanned to create two-dimensional images. The precursors were obtained after layer stacking processes. A full ceramic sample was obtained through heat treatment processes. Fine hydroxyapatite microstructures without cracks were observed by using a scanning electron microscope. This result shows that stereolithography is a novel technology that can be used to fabricate bio-scaffolds. The successfully manufactured bone substitute and the strictly designed bioscaffold structures can be used to promote appropriate biochemical reactions and body fluid circulation in the near future through tissue engineering.