抄録
A 27 MHz piezoelectric crystal was connected with a network analyzer. Both a frequency shift (ΔF) and energy dissipation change (ΔD) were observed when biomolecules were immobilized on a piezoelectric plate. Linear biomolecules such as DNA strands showed a large energy dissipation due to their flexible structures and the amount of hydrated water. On the contrary, globular proteins showed a small energy dissipation, which means proteins are relatively rigid. The combination of a piezoelectric crystal and a network analyzer will provide a powerful tool to analyze the hydration and viscoelasticity of biomolecules.
