バイオセンサーと表面化学

抄録

Worldwide reseach on biosensors is growing rapidly, with new advances. Many papers on fundamental and applied aspects are appearing weekly. For the further development of biosensors, especially for the clinical uses, new challenges to microfabrication of biosensors with high performance such as high selectivity, high sensitivity, and satisfactory stability for intelligent, multipurpose clinical autoanalyzers are strongly required. Also a great excitation exists for using in vivo biosensors in connection with the development of artificial organs. For this purpose biomaterials should provide biocompatibility. This article describes the concepts of biosensors and the material science of biosensors from the veiwpoint of effective signal transduction, sensitization and microfabrication. In addition, the importance of surface chemistry is emphasized for the development of biocompatible implantable biosensors.