Gene Transfer to Cerebral Blood Vessels: What's the Future?

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Gene transfer to blood vessels is an effective approach to alter vasomotor function, and a useful tool for studying vascular biology. Gene therapy for cerebrovascular diseases is an attractive approach, especially when pharmacological approaches are not effective. Preliminary data suggest that gene therapy may be useful for prevention of cerebral vasospasm after subarachnoid hemorrhage. As better ventors are developed, other clinical problems also may become targets for gene therapy.