Possible roles of endogenous RNA virus elements in RNA virus infection

Abstract

While ebola virus disease (EVD) outbreak in West Africa seemed to be subsided, there are still some sporadic cases reported from the field.
Many studies were conducted during the outbreak. It was identified that the virus can survive for a long period in certain areas of the survivors and they can be a reservoir. But the mechanism is still unknown. Currently no specific drug for EVD is established and classic supportive therapy was the mainstay of the treatment. A new ebola vaccine candidates appear to be highly effective for post-exposure prophylaxis. Rapid diagnostic tests are under development.
In West Africa, Ebola response and recovery efforts to achieve and to sustain a "resilient zero" are ongoing. The situation in the communities is stabilized but ebola survivors are still suffering both from stigma and sequelae.
EVD outbreak damaged affected countries' health, economic and education systems. The risk of re-outbreak is still remained. It is important to strengthen comprehensive public health system to prevent the future emerging disease outbreaks.