STUDIES ON HEMAGGLUTINATING ACTIVITY, INFECTIVITY AND IMMUNIZING ABILITY OF INFLUENZA VIRUS

iv STUDIES ON THE GROWTH OF EGG-ADAPTED LINES OF INFLUENZA VIRUS FM1, WHICH ARE NONPATHOGENIC TO MICE, IN THE LUNG OF MICE

Abstract

We studied if egg-adapted lines of influenza virus FM1 are non-pathogenic to mice but grow in the lung of mice. We saw that egg-adapted lines FM1 which are subculturer in eggs for many generations survived in the lung of mice for some days after intranasal inoculation, but we did not recognize the production of egg-adapted lines of influenza virus FM1 in the lung of mice.