Journal of Traditional Medicines
Online ISSN : 1881-3747
Print ISSN : 1880-1447
ISSN-L : 1880-1447
Short Communication
Analysis of phthalate derivatives in Kampo medicinal products
Chie YAMASAKIMitsuko MAEDAHiroyuki HIRANO
Author information
JOURNALS FREE ACCESS

2009 Volume 26 Issue 2 Pages 93-96

Details
Abstract

Recently, food safety has become an increasingly important issue in Japan. Currently, most natural medicines used in Japan are dependent on imports from China. In the future, further economic development of China is expected, and various materials are produced will be released throughout the environment. In this study, we paid increased attention to the phthalate derivatives, and performed quantitative analysis by HPLC of extractions through boiling of five kinds of natural medicines and the extraction of 18 kinds of Kampo medicinal products. As a result, 7 kinds of phthalate derivatives except bis-2-ethylhexyl phthalate (DEHP) were detected in natural medicines. Among Kampo medicinal products, di-n-butyl phthalate (DBP) was detected in all products tested except daikenchuto and keigairengyoto, high levels of diethyl phthalate (DEP) was detected in shoseiryuto and di-n-pentyl phthalate (DPP) and DEHP were detected only in tokishakuyakusan. di-n-hexyl phthalate (DnHP) was not detected in any of the Kampo medicinal products tested.

Information related to the author
© 2009 Medical and Pharmaceutical Society for WAKAN-YAKU
Previous article
feedback
Top