The Journal of Toxicological Sciences
Online ISSN : 1880-3989
Print ISSN : 0388-1350
ISSN-L : 0388-1350
Toxicogenomics/proteomics Report
Overexpression of Ycg1 or Ydr520c confers resistance to cadmium in Saccharomyces cerevisiae
Gi-Wook HwangKanae SasakiTsutomu TakahashiReiko YamamotoAkira Naganuma
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2009 Volume 34 Issue 4 Pages 441-443

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Abstract

We introduced a yeast open reading frame library into Saccharomyces cerevisiae strain BY4742 to search for genes whose overexpression conferred cadmium resistance to yeast, toward the goal of elucidating the mechanism of cadmium toxicity. As a result, we found that the overexpression of two newly identified genes, Ycg1 and Ydr520c, each conferred strong cadmium resistance to yeast.

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© 2009 The Japanese Society of Toxicology
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