Author's Organization:Korea Research Institute of Bioscience and Biotechnlolgy Korea Research Institute of Bioscience and Biotechnlolgy Korea Research Institute of Bioscience and Biotechnlolgy Korea Research Institute of Bioscience and Biotechnlolgy Korea Research Institute of Bioscience and Biotechnlolgy Korea Research Institute of Bioscience and Biotechnlolgy Korea Research Institute of Bioscience and Biotechnlolgy