東京女子医科大学雑誌
Online ISSN : 2432-6178
Print ISSN : 0040-9022
ISSN-L : 0040-9022
原著
アドレナリン自己注射薬(エピペン)の処方例と使用例の患者背景調査
東 範彦大谷 智子野中 早苗小谷 碧二瓶 聡美竹下 淳子伊藤 幸栄國井 優子萩原 幸世竹下 英里松岡 典子杉原 茂孝
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2017 年 87 巻 Extra1 号 p. E80-E87

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Objective: In recent years, food allergy has become a social problem, and its relationship with anaphylaxis is very important. The epinephrine auto-injector EpiPen® is valuable in anaphylaxis treatment. We analyzed EpiPen® usage in patients with food allergy.

Method: We analyzed 187 pediatric patients prescribed EpiPen® in our department from 2005 to 2014.

Results: The number of patients prescribed EpiPen® increased 2012, after a case of death from food-allergy-induced anaphylaxis occurred in Japan. The major reason for EpiPen® prescription is a history of immediate reactions (IR, 84 %), followed by a history of food-dependent exercise-induced anaphylaxis (FDEIA, 11 %). EpiPen® was used in 21 cases (19 patients). FDEIA cases are 9 cases (40 %). EpiPen® was injected by patient self in 7 cases, by parent in 12 cases,by faculty member in 1 case and by ambulance attendant in 1 case. Discussion: In the FDEIA group, the patients themselves are responsible for their anaphylaxis treatment. We souhld educate not only the guardians but also the patients in cases where EpiPen® is prescribed for FDEIA.

Conclusion: It is important to figure out the peculiarity of the cases of EpiPen® was used and construct ambulance system.

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