Osteomyelitis of the Temporal Bone Caused by Zygomycetes in a Shoat

Abstract

On a pig fattening farm in Akita， Japan， a 40-day-old castrated shoat showed eminence of the left temporal area and growth delay， and was humanely put down. At necropsy， the cut surface of a mass in the temporal bone was composed of multifocal yellowish white necrotic foci and abundant white connective tissue. Histologically， the lesion consisted of multifocal granulomatous osteomyelitis with numerous fungal hyphae. The fungal hyphae were positively immunolabeled with a monoclonal antibody against Rhizopus arrhizus. On the basis of these findings， this case was diagnosed as granulomatous osteomyelitis caused by zygomycetes.