Journal of the Japan Veterinary Medical Association
Online ISSN : 2186-0211
Print ISSN : 0446-6454
ISSN-L : 0446-6454
The Japanese Society of Small Animal Veterinary Medicine
Treatment with Lomustine for Mediastinal Lymphoma in a Rabbit
Mamoru ONUMA, Hirotaka KONDO, Megumi ISHIKAWA, Sadaharu ONO, Mariko UEKI, Hisashi SHIBUYA, Tsuneo SATO
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Keywords: Lomustine, lymphoma, rabbit
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2009 Volume 62 Issue 1 Pages 69-71

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Abstract

A rabbit (Oryctolagus cuniculus) with leukemic mediastinal lymphoma，which had not responded to steroid therapy，received the alkylating agent Lomustine (50 mg/m2) twice at 21-day intervals until complete remission was achieved. No serious side effects were encountered， other than a slight increase in serum ALP level. The rabbit died due to renal failure 91 days after the second administration of Lomustine. The survival time was 128 days in this case.

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© 2009 Japan Veterinary Medical Association
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