2010 Volume 63 Issue 9 Pages 715-718
A seven-month-old cat with severe neurological symptoms was diagnosed with non-effusive feline infectious peritonitis (FIP) following a pathological examination. Grossly, the brain showed marked congestion and edema. Multiple creamy white nodules were located in the renal cortex. Histologically, pyogranulomatous lesions were found in the renal cortex and the central nervous system (CNS) parenchyma around the ventricles and choroid plexus, whereas a fibrin thrombus in the sinus of dura mater and diffuse congestion were observed in the cerebrum. FIP virus-positive immunolabelings were detected in the cytoplasm of the macrophages in the lesions. These findings suggest that inflammation located in the periventricular areas and choroid plexus due to FIP virus infection induced fibrin thrombus formation, leading to a circulatory disturbance in the sinus of the dura mater.
