The Utility of Serum 1α,25-dihydroxyvitaminD Values in a Dog with Primary Hyperparathyroidism

Abstract

The concentration of 1α,25-dihydroxyvitaminD [1,25(OH)₂D], was measured in a Welsh Corgi Pembroke with a primary hyperparathyroidism (PHP). The serum concentration of 1,25(OH)₂D was 242 ± 55 pg/ml(mean ± SD, total of seven measurements) in the dog with PHP and 98 ± 30 pg/ml in clinically normal dogs (n ＝8). In the dog with PHP, the serum concentration of 1,25(OH)₂D decreased after surgical removal of a parathyroid mass. These findings suggest that the elevation of serum 1,25(OH)₂D concentration could be a useful marker for evaluating the diagnosis of a dog with PHP.