The anthelmintic efficacy of thiabendazole was evaluated in field tests on 34 cattle and critical tests on 8 chickens.
A dose of 50mg of thiabendazole per kg of body weight, given in a drench or a ration, was not sufficient to remove parasites of the genera Haemonchus, Mecistocirrus Ostertagia, Cooperia, and Nematodirrus from cattle. A dose of 100mg/kg, given in a drench, showed a considerable efficacy against these parasites. Both doses had little effect upon worms of Trichuris and Moniezia. The drug was proved to be safe for use in cattle.
When administered orally to chickens, 100mg/kg of thiabendazole had a low efficacy and 300mg/kg an uncertain efficacy in removing Ascaridia galli, but 500mg/kg showed complete effectiveness against this species. These three doses had little effect on
Heterakis
gallinae. The drug might not be promising because of its relatively high dose rate, though it was proved to be safe for use in chickens.
