Simple Determination of Blood Plasma Fibrinogen by Salting-out and Nephelometry in Cattle and Dogs

Abstract

There was a distinct correlation in the results of determination of blood plasma fibrinogen between the method using salting-out and nephelometry (SN method) and the tyrosine method. The SN method was of high reproducibility and available for determination of blood plasma fibrinogen in cattle and dogs.
Blood plasma samples obtained with seven conventionally used anticoagulants could be employed for the SN method. When sodium citrate solution was applied to this method, the fibrinogen determined. was lower in level than that determined by the method with any one of the seven anticoagulants.
The SN method was applicable to the veterinary practice, since it required a shorter time and simpler techniques for determination than the tyrosine method.