1981 Volume 34 Issue 2 Pages 54-58
Prostaglandin F2α (PGF) was injected intramuscularly into 76 cows suffering from uterine diseases with persistent corpus luteum. The results obtained are as follows.
1. Fetal death (mummification and maceration of the fetus) occurred in 25 of 27 cows within 3 days after treatment with 10-30mg of PGF.
2. Pyometra was treated successfully in four of 10 cows.
3. Estrus recurred and conception was caused by A. I. in 3 cows with myxometra injected with 12mg of PGF.
4. Retained lochia was evacuated in 33 cows 2-7 days after treatment.
5. Postendometritis with persistent corpus luteum was treated successfully in 5 cows given 12mg of PGF.
6. Progesterone levels in the plasma were below 1 ng/ml in all animals 1 day after PGF injection, though they were 3-7ng/ml at the time of PGF treatment. These results suggest that PGF may be effective against luteolysis with symptoms.