1984 Volume 37 Issue 5 Pages 293-297
Clinical and clinicopathological observations were carried out on a heifer 25 months old which showed poor growth for about one year. The main symptoms were marked emaciation, poor appetite, diarrhea, polydypsia and polyuria. Biochemical studies of blood and urine indicated persistent hyperglycemia, intolerance in the glucose tolerance test, glucosuria, and ketonuria.
Pathological examination revealed atrophy of islets of Langerhans and degeneration and disappearance of B cells in the pancreas. From these findings a diagnosis of diabetes mellitus was made in this heifer.