1986 Volume 39 Issue 3 Pages 181-184
Calf-type bovine leukosis developed in female twin Holstein-Freisian calves. The markings of the hair coat were not similar. Clinically, both calves showed swelling of body surface lymphnodes, fervescence, emaciation, and diarrhea. A large number of immature lymphocytes appearted in the peripheral blood.
The animals died at 155 days (No.1) and 199 days of age (No.2). Enlargement was seen in the following lymphatic organs: the thymus, lymphnodes of the body surface, endothoracic and intracelial lymphnodes, spleen, and kidneys as well. Microscopically, immature neoplastic lymphocytes infiltrated the lymphnodes, liver, spleen, kidneys, lung, and bone marrow. In praticular, the neoplastic lymphocytes infiltrated the Glisson's sheeths of the liver. As reported previously this seemed to be one of the distinctive features of calf-type Bovine Leukosis. In addition, Bovine Leukosis Virus (BLV) antigens were not detected in their serum.
