Journal of the Japan Veterinary Medical Association
Online ISSN : 2186-0211
Print ISSN : 0446-6454
ISSN-L : 0446-6454
Intracerebral Cryptococcosis in a Cat Treated by Surgery and Chemotherapy
HOZUMI YAMAMURA[in Japanese][in Japanese][in Japanese][in Japanese][in Japanese]
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1986 Volume 39 Issue 7 Pages 432-436


A three-year-old female domestic short-haired cat was presented with dyspnea and dysbasia. A diagnosis of intracerebral cryptococcosis was made in it.
A focus located in the area of the right anterior cerebral artery was revealed by brain angiography. It consisted of gray white mass and removed surgically. Yeast cells with a capsule were detected in mycological and histopathological examinations.
At first, amphotericin B (1 mg/kg) was administered intravenously every three days. The cat recovered clinically. Serum agglutination titer for cryptococcal antigen, however, was still high after 14 injections. Then treatment was donewith a combin ation of amphotericin B (0.5mg/kg, i. v., every other day) and 5-fluorocytosin (94 mg/kg, p.o., every day) for one month. The titer became almost negative after ten months.

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