1987 Volume 40 Issue 7 Pages 513-518
In December, 1985, abnormal and stillborn young were found in 26 neonates of 21 litters out of 37 neonates of 30 litters born from Suffolk ewes on 5 sheep farms in Aomori Prefecture. Six abnormal young showed almost the same symptoms, such as bending and crooking of the joints, including the fetlocks, of the four extremities, sigmoid rachiocampsis, hydrocephalus, glial nodule of the cerebrum, and degeneration and winding of skeletal muscle fibers. When determined, Akabane virus neutralizing antibody titer was 1: 64 in a neonate before having colostrum, 1: 16-1: 32 in 3 neonates after having colostrum, and 1: 8-1: 256 in 19 ewes raised in the same barn as the dams. It was concluded that the abnormal and stillborn young had been produced by infection with Akabane disease virus.