1988 Volume 41 Issue 10 Pages 731-734
Bovine respiratory disease occured on T dairy farm in Saitama prefecture in April, 1986. Nine cattle of two herd introduced to the farm before two weeks were shown respiratory symptons and other signs. One of them died and other recovered. In necropsy, carcase revealed fibrinous pneumoniae.
Histopathologically, the interlobular septum, broncholes, and alveoli filled with fibrin, edematous fluid, macrophages, neutrophils and erythrocytes.
Pasteurella haemolytica was isolated in pure culture from lungs. The isolate was determined to be serover 1 and biovar A, and has sensitive to AB-PC, PC, KM and TC.
Serum agglutinin titers againstP. haemolyticain affected cattle, including the one that died, ranged from 1: 10 to 40 at introduction, and increased to 1: 160≥1:640 2 weeks later. Furthermore, neutralization antibody titers against Bovine RS virus increased, however, Bovine adeno-7 virus, PI-3 virus, IBR virus and Bovine Rhino virus were unchanged.
Mycoplasmas and viruses were not isolated from the lung or cerebrum of the carcase.
From these results, the disease was diagnosed as P. haemolytica infection, associated with BRS virus infection as inducer.
