A Case of Amyloidosis in a Dairy Cow

Abstract

Clinical and pathological findings on the amyloidosis of a dairy cow are described. A 79 monthold cow showed lack of appetite, watery diarrhea, emaciation, cutaneous edema and proteinuria after parturition, and was slaughtered at 29 days of illness. Biochemically, hypoproteinemia, decreased albumin, and increased α and γ globulin were observed. Histopathologically, severe amyloid deposits were observed in the Disse's spaces of the liver associated with diminished amyloid deposition in the renal glomeruli.