Journal of the Japan Veterinary Medical Association
Online ISSN : 2186-0211
Print ISSN : 0446-6454
ISSN-L : 0446-6454
Evaluation of 1% Pimaricin Suspension on Canine Otitis Externa Caused by Fungi
Yoshiko UCHIDAYoshihisa YAMANETetsuya NAKADEKanjuro OTOMO
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1994 Volume 47 Issue 10 Pages 762-764


The efficacy of 1% pimaricin suspension was evaluated to canine otitis externa related with yeast-like fungi. Dogs were diagnosed as otitis externa associated with the fungi from clinical examination using a otoscope and microbiological tests. This drug was administrated 4 or 5 drops into ear canals twice a day for 2 weeks. One hundred and forty-five cases were evaluated for the safety and 70 of them were evaluated for the clinical efficacy. Clinical responses were classified into 4 categories; very good, good, fair, and poor. In 145 cases examined, no significant side effects were observed during the therapy. The symptoms of otitis externa were ameliorated steadily by the therapy. After the therapy, 16 cases belonged to the group of very good response, 35 cases belonged to good, 12 cases belonged to fair and 7 cases belonged to poor. Satisfactory responses were clinically observed in 72.9%.

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