1999 Volume 52 Issue 6 Pages 374-377
A 8-month-old Shiba dog with chronic anorexia and vomition was shown to have hepatomegaly by radiography and cystic dilation of the intrahepatic bile ducts by cholangiography. Contrast medium was accumulated within the renal medulla on intravenous urography, and ultrasonography revealed protrudent blood vessels within the dilated and cystic bile ducts. After euthanasia hyperplasia of cholangioepitheliocytes, hepatic fibrosis and dilation of the uriniferous tubules were observed histologically. These findings were similar to those observed in human Caroli desease.