Repeated Early Abortions in One Cow

Abstract

Pathohistological and immunohistochemcial investigations of 2 premature fetuses (fetal ages 113 and 129 days) aborted by the same cow within 6 months on a dairy farm showed multifocal necrosis invaded by microglia that were negative for the GFAP (glial fibrillary acidic protein) antigen and slightly positive for the CD (clusters of differentiation) 68 antigen. Immunohistochemcial staining revealed a proliferation of tachyzoites positive for the antibody against theNeospora caninumNC-1 strain in necrotic lesions in the liver, kidneys, and allantoic stalk. Necrotic lesions in the allantoic stalk were thought to be one of the causes of early abortion.