Journal of the Japan Veterinary Medical Association
Online ISSN : 2186-0211
Print ISSN : 0446-6454
ISSN-L : 0446-6454
Systemic Amyloidosis with Hepatic Rupture in Two Cats
Atsuko KOJIMOTOTeruo ITOHKazuyuki UCHIDAYasuyuki ENDOHiroki SHII
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2008 Volume 61 Issue 5 Pages 382-385


Hepatic rupture and hemoperitoneum were found in postmortem examinations of two cats seropositive forfeline leukemia virus. One cat had clinically shown severe enlargements of the liver and kidneys, severe hyperbilirubinemia, and cytological findings indicative of renal lymphoma, and had died without responding tochemotherapy. Another cat had been receiving treatments for chronic anemia due to myelodysplastic syndrome, and had died showing hyperbilirubinemia. In both cases, histopathological examinations revealedsevere amyloid deposits in the liver. Milder amyloid deposits were also found in the kidney and other organs, and a diagnosis of systemic amyloidosis was made. Hepatic ruptures in these two cats were thought to be associatedwith amyloidosis.

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