2008 Volume 61 Issue 7 Pages 543-548
Fifty seven canine and 26 feline cases of malignant lymphoma were reviewed histopathologically and by immunohistochemistry and flow-cytometry using T-and B-cell markers. Based on these results, each case was diagnosed according to the WHO 2nd classification of malignantlymphoma of domestic animals. Anatomical classification was also conducted. In both animals, B-cell lymphomas were predominant in up to two-thirds of all cases. In particular, large B-cell lymphoma accounted for one-third of the cases. Of T/NK cell lymphomas, large granular lymphoproliferative disorders were most common in both dogs and cats. More than halfof canine lymphomas were multicentric forms, while feline lymphomas were observed in various organs.