Lomustine for the Treatment of Alimentary Lymphoma as a Rescue Protocol for Ferrets

Abstract

A ferret (Mustela putorius furo) with alimentary lymphoma that showed resistance to combination chemotherapywas administered an alkylating agent, Lomustine, as the rescue therapy and achieved complete remission.Lomustine was administered at a dosage of 50 mg/m² in a total of two doses at 28-day intervals, until remissionwas achieved. No marked toxic effects were observed. Remission duration after rescue therapy was 160 days.It was suggested that Lomustine could be considered a rescue protocol option for lymphoma in ferrets, as wellas in cats and dogs.