1999 年 61 巻 8 号 p. 979-981
The aim of the present study was to examine the LH response to exogenous estradiol in 4 heifers with ACTH-induced ovarian follicular cysts. During the control experiment, administration of estradiol 24 hr after PGF2α in luteal phase heifers resulted in a LH response in all 4 heifers. The LH response was obtained between 16-20 hr after estradiol administration. The peak LH concentration (Mean ± SEM; 5.1 ± 0.8 ng/ml) during the control study was significantly different (P<0.05) from the concentration after cyst formation. None of the 4 heifers responded to estradiol after ovarian cyst formation. This result suggests that heifers with ACTH-induced ovarian follicular cysts may have a defective hypothalamio-pituitary response to exogenous estradiol similar to cows with spontaneous ovarian cysts.
