Journal of Veterinary Medical Science
Online ISSN : 1347-7439
Print ISSN : 0916-7250
ISSN-L : 0916-7250
Effects of Repeated Atropine Injection on Heart Rate Variability in Thoroughbred Horses
Hajime OHMURAAtsushi HIRAGAHiroko AIDAMasayoshi KUWAHARAHirokazu TSUBONE
ジャーナル フリー

2001 年 63 巻 12 号 p. 1359-1360


To investigate the effects of repeated atropine injection on heart rate (HR) variability in resting Thoroughbred horses, two μg/kg of atropine as parasympathetic nervous blockade was injected intravenously every 6 min to a total of 8 μg/kg after intravenous administration of 0.2 mg/kg of propranolol as sympathetic nervous blockade. We recorded electrocardiograms and obtained the HR, then evaluated variation in HR from the power spectrum in terms of low frequency (LF, 0.01-0.07 Hz) power and high frequency (HF, 0.07-0.6 Hz) power. Administration of atropine decreased parasympathetic nervous activity in a dose-dependent manner, affecting first the LF power, then the HF power and finally HR. These responses may provide valuable information for evaluating autonomic nervous activity in Thoroughbred horses.


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