Anti-anxiety Effect of Ovary Lipid Extracted from Skipjack Tuna (Katsuwonus pelamis) in Rats

Katumasa OOKAWA; Kazuo MOCHIZUKI; Eiji SHIDA; Toshihiro SUZUKI; Toshihiro SUZUKI; Tomoko OOBA; Toru MATUMOTO; Yoshinori HOKARI; Masayuki HASHIDUME; Hidehiko YOKOGOSHI

doi:10.1292/jvms.69.633

NOTE

Anti-anxiety Effect of Ovary Lipid Extracted from Skipjack Tuna (Katsuwonus pelamis) in Rats

Katumasa OOKAWA, Kazuo MOCHIZUKI, Eiji SHIDA, Toshihiro SUZUKI, Toshihiro SUZUKI, Tomoko OOBA, Toru MATUMOTO, Yoshinori HOKARI, Masayuki HASHIDUME, Hidehiko YOKOGOSHI

Author information

Katumasa OOKAWA
Industrial Research Institute of Shizuoka Prefecture
Kazuo MOCHIZUKI
Industrial Research Institute of Shizuoka Prefecture
Eiji SHIDA
Industrial Research Institute of Shizuoka Prefecture
Toshihiro SUZUKI
Industrial Research Institute of Shizuoka Prefecture
Toshihiro SUZUKI
Industrial Research Institute of Shizuoka Prefecture
Tomoko OOBA
Maruhachi Muramatsu, Inc.
Toru MATUMOTO
Maruhachi Muramatsu, Inc.
Yoshinori HOKARI
Maruhachi Muramatsu, Inc.
Masayuki HASHIDUME
Maruhachi Muramatsu, Inc.
Hidehiko YOKOGOSHI
University of Shizuoka

Keywords: anxiety, elevated plus-maze test, ovary lipid

JOURNAL FREE ACCESS

2007 Volume 69 Issue 6 Pages 633-636

DOI https://doi.org/10.1292/jvms.69.633

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Abstract

Using an elevated plus-maze test, we evaluated anxiety level in rats given ovary lipid extracted from Skipjack tuna (Katsuwonus pelamis; OLS). The percentage of open time was significantly higher in rats given OLS than in rats in the control group, but lower than in rats given diazepam (1.0 mg/kg body weight). Based on this fact and findings about other indicators, this study showed that OLS does not have as fast-acting and strong an anti-anxiety effect as diazepam but that continuous ingestion of OLS causes an anti-anxiety effect in animals.

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