Journal of Veterinary Medical Science
Online ISSN : 1347-7439
Print ISSN : 0916-7250
Clinical Pathology
Eosinophilia and Eosinophilic Infiltration into Splenic B-Cell High-Grade Lymphoma in a Dog
Hirotaka TOMIYASUYasuhito FUJINOJun UGAIYuko GOTO-KOSHINOTetsuya IDEMasashi TAKAHASHIKoichi OHNOKazuyuki UCHIDAHiroyuki NAKAYAMHajime TSUJIMOTO
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2010 Volume 72 Issue 10 Pages 1367-1370

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Abstract

A 13-year-old mixed-breed dog showing ascites, anorexia and anemia was found to have leukocytosis with marked eosinophilia, splenomegaly and hepatomegaly. The dog died 4 days after initial presentation and was diagnosed with splenic high-grade B-cell lymphoma at necropsy. Remarkable infiltrations of eosinophils were observed in spleen and liver tissues. The eosinophilia and infiltration of eosinophils into the lesions could have been associated with B-cell lymphoma because causes other than lymphoma were excluded. This is the first report of eosinophilia and eosinophilic infiltrations into neoplastic lesions in a dog with high-grade B-cell lymphoma.

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