Seroprevalence of BV (Macacine Herpesvirus 1) in Bred Cynomolgus Monkeys in Cambodia

Abstract

The seroprevalence of B Virus (BV, Macacine herpesvirus 1) in bred cynomolgus monkeys (Macaca fascicularis) in Cambodia was investigated. Blood samples were collected by venous puncture between 2007 and 2011, and a commercially available enzyme-linked immunosorbent assay (ELISA) kit was used to detect IgG antibodies against BV. A total of 1710 blood samples were examined, and the overall prevalence of BV antibodies was 33.92% (580/1710). The young adult (2-6 years) monkeys had a seroprevalence of 30.57% (497/1626), and the older (>7 years) monkeys had a seroprevalence of 98.81% (83/84). The present investigation revealed that the prevalence of BV antibodies in bred cynomolgus monkeys was highly correlated with their age, with higher prevalence in older monkeys in Cambodia.