Protective efficacy of stockpiled vaccine against H5N8 highly pathogenic          avian influenza virus isolated from a chicken in Kumamoto prefecture, Japan, in          2014

Koichiro GAMOH; Mari NAKAMIZO; Masatoshi OKAMATSU; Yoshihiro SAKODA; Hiroshi KIDA; Shoko SUZUKI

doi:10.1292/jvms.15-0324

Avian Pathology

Protective efficacy of stockpiled vaccine against H5N8 highly pathogenic avian influenza virus isolated from a chicken in Kumamoto prefecture, Japan, in 2014

Koichiro GAMOH, Mari NAKAMIZO, Masatoshi OKAMATSU, Yoshihiro SAKODA, Hiroshi KIDA, Shoko SUZUKI

著者情報

Koichiro GAMOH
National Veterinary Assay Laboratory, Ministry of Agriculture, Forestry and Fisheries, 1–15–1 Tokura, Kokubunji, Tokyo 185–8511, Japan
Mari NAKAMIZO
National Veterinary Assay Laboratory, Ministry of Agriculture, Forestry and Fisheries, 1–15–1 Tokura, Kokubunji, Tokyo 185–8511, Japan
Masatoshi OKAMATSU
Laboratory of Microbiology, Department of Disease Control, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo 060–0818, Japan
Yoshihiro SAKODA
Laboratory of Microbiology, Department of Disease Control, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo 060–0818, Japan
Research Center for Zoonosis Control, Hokkaido University, Sapporo 001–0020, Japan
Hiroshi KIDA
Laboratory of Microbiology, Department of Disease Control, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo 060–0818, Japan
Research Center for Zoonosis Control, Hokkaido University, Sapporo 001–0020, Japan
Global Station for Zoonosis Control, Global Institution for Collaborative Research and Education (GI-CoRE), Hokkaido University, Sapporo 001–0020, Japan
Shoko SUZUKI
National Veterinary Assay Laboratory, Ministry of Agriculture, Forestry and Fisheries, 1–15–1 Tokura, Kokubunji, Tokyo 185–8511, Japan

キーワード: disease control, efficacy, highly pathogenic avian influenza, low pathogenic avian influenza, vaccine

ジャーナルフリー

2016 年 78 巻 1 号 p. 139-142

DOI https://doi.org/10.1292/jvms.15-0324

Browse “Advance online publication” version

詳細

抄録

H5 highly pathogenic avian influenza (HPAI) viruses have spread worldwide, and antigenic variants of different clades have been selected. In this study, the national stockpiled vaccine prepared from A/duck/Hokkaido/Vac-1/2004 (H5N1) strain was evaluated for the protective efficacy against H5N8 HPAI virus isolated in Kumamoto prefecture, Japan, in April 2014. In the challenge test, all of the vaccinated chickens survived without showing any clinical signs and reduced virus shedding. It was concluded that the present stockpiled vaccine was effective against the H5N8 HPAI virus.

責任著者(Corresponding author)

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