Journal of Veterinary Medical Science
Online ISSN : 1347-7439
Print ISSN : 0916-7250
ISSN-L : 0916-7250
Virology
Full genome analysis of bovine papillomavirus type 1 derived from a calf with severe cutaneous multiple papillomatosis
Hidekatsu SHIMAKURAJianbao DONGWei ZHUJames K. CHAMBERSKazuyuki UCHIDAKensuke KIRIKIMizuho UEMATSUYoshitaka GOTOMasahiro YASUDANanako YAMASHITA-KAWANISHIMasano TSUZUKIDung T. LEShinichi HATAMATakeshi HAGA
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2018 年 80 巻 11 号 p. 1691-1695

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Severe papillomatosis occasionally causes astasia leading to euthanizing cattle. There are currently a limited number of reports on virologic approach in severe bovine papillomatosis. Here we report a full genome characterization of bovine papillomavirus type 1 (BPV-1) from the case of severe papillomatosis. A calf developed numerous papillomas on the skin and some nodules in the upper gastrointestinal tract at seven months old. The skin lesion was diagnosed as the epithelial papilloma with BPV antigen expression, while the gastrointestinal lesions were diagnosed as the fibropapilloma without BPV antigen. Full genome analysis revealed that BPV-1s detected in all the lesions were exactly the same. Compared with the reference BPV-1 sequence, there was a single nucleotide insertion in the upstream regulatory region.

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この記事はクリエイティブ・コモンズ [表示 - 非営利 - 改変禁止 4.0 国際]ライセンスの下に提供されています。
https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja
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