Squamous cell carcinoma of unknown primary origin in a dog presenting with          bone metastasis

Oscar Rodrigo SIERRA MATIZ; Rafaela Bortolotti VIERA; Paulo Cesar JARK; Denner Santos DOS ANJOS; Julio Edward Hough MONTEIRO; Andresa MATSUI; Rosemeri de Oliveira VASCONCELOS; Felipe Ruiz SUEIRO; Sabryna Gouveia CALAZANS; Mirela TINUCCI-COSTA

doi:10.1292/jvms.18-0594

Internal Medicine

Squamous cell carcinoma of unknown primary origin in a dog presenting with bone metastasis

Oscar Rodrigo SIERRA MATIZ, Rafaela Bortolotti VIERA, Paulo Cesar JARK, Denner Santos DOS ANJOS, Julio Edward Hough MONTEIRO, Andresa MATSUI, Rosemeri de Oliveira VASCONCELOS, Felipe Ruiz SUEIRO, Sabryna Gouveia CALAZANS, Mirela TINUCCI-COSTA

著者情報

Oscar Rodrigo SIERRA MATIZ
Clinic and Surgery Department, College of Agricultural and Veterinarian Science, São Paulo State University, UNESP 14884-900, Jaboticabal, SP, Brazil
Rafaela Bortolotti VIERA
Clinic and Surgery Department, College of Agricultural and Veterinarian Science, São Paulo State University, UNESP 14884-900, Jaboticabal, SP, Brazil
Paulo Cesar JARK
Clinic and Surgery Department, College of Agricultural and Veterinarian Science, São Paulo State University, UNESP 14884-900, Jaboticabal, SP, Brazil
Denner Santos DOS ANJOS
Clinic and Surgery Department, College of Agricultural and Veterinarian Science, São Paulo State University, UNESP 14884-900, Jaboticabal, SP, Brazil
Julio Edward Hough MONTEIRO
Pathology Department, College of Agricultural and Veterinarian Science, São Paulo State University, UNESP 14884-900, Jaboticabal, SP, Brazil
Andresa MATSUI
Pathology Department, College of Agricultural and Veterinarian Science, São Paulo State University, UNESP 14884-900, Jaboticabal, SP, Brazil
Rosemeri de Oliveira VASCONCELOS
Pathology Department, College of Agricultural and Veterinarian Science, São Paulo State University, UNESP 14884-900, Jaboticabal, SP, Brazil
Felipe Ruiz SUEIRO
VETPAT, Veterinary Pathology Laboratory, 13073-022 Campinas, SP, Brazil
Sabryna Gouveia CALAZANS
Clinic and Surgery Department, College of Agricultural and Veterinarian Science, São Paulo State University, UNESP 14884-900, Jaboticabal, SP, Brazil
Mirela TINUCCI-COSTA
Clinic and Surgery Department, College of Agricultural and Veterinarian Science, São Paulo State University, UNESP 14884-900, Jaboticabal, SP, Brazil

キーワード: canine, carcinoma of unknown primary, metastatic cancer, neoplasm

ジャーナルフリー

2019 年 81 巻 8 号 p. 1177-1181

DOI https://doi.org/10.1292/jvms.18-0594

Browse “Advance online publication” version

詳細

抄録

A 10-year-old female American Pit Bull dog was diagnosed with metastatic undifferentiated carcinoma of the scapula. Immunohistochemistry showed positive immunoexpression for cytokeratins (AE1/AE3, 34BE12, CK7) and vimentin, confirming squamous cell carcinoma. No evidence of nodules was found in the complete physical examination and imaging procedures conducted. The patient was diagnosed with carcinoma of unknown primary origin. Amputation and adjuvant chemotherapy with doxorubicin and piroxicam were performed, but the patient died of respiratory failure after 737 days of diagnosis. Necropsy confirmed undifferentiated carcinoma infiltrating the lungs and kidneys, and showing the same immunoexpression as the tumor in the scapula. Amputation associated with chemotherapy extended the overall survival time of this patient.

責任著者(Corresponding author)

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