Journal of Veterinary Medical Science
Online ISSN : 1347-7439
Print ISSN : 0916-7250
ISSN-L : 0916-7250
Internal Medicine
Squamous cell carcinoma of unknown primary origin in a dog presenting with bone metastasis
Oscar Rodrigo SIERRA MATIZRafaela Bortolotti VIERAPaulo Cesar JARKDenner Santos DOS ANJOSJulio Edward Hough MONTEIROAndresa MATSUIRosemeri de Oliveira VASCONCELOSFelipe Ruiz SUEIROSabryna Gouveia CALAZANSMirela TINUCCI-COSTA
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2019 年 81 巻 8 号 p. 1177-1181

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A 10-year-old female American Pit Bull dog was diagnosed with metastatic undifferentiated carcinoma of the scapula. Immunohistochemistry showed positive immunoexpression for cytokeratins (AE1/AE3, 34BE12, CK7) and vimentin, confirming squamous cell carcinoma. No evidence of nodules was found in the complete physical examination and imaging procedures conducted. The patient was diagnosed with carcinoma of unknown primary origin. Amputation and adjuvant chemotherapy with doxorubicin and piroxicam were performed, but the patient died of respiratory failure after 737 days of diagnosis. Necropsy confirmed undifferentiated carcinoma infiltrating the lungs and kidneys, and showing the same immunoexpression as the tumor in the scapula. Amputation associated with chemotherapy extended the overall survival time of this patient.

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この記事はクリエイティブ・コモンズ [表示 - 非営利 - 改変禁止 4.0 国際]ライセンスの下に提供されています。
https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja
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