Journal of Veterinary Medical Science
Online ISSN : 1347-7439
Print ISSN : 0916-7250
ISSN-L : 0916-7250
Wild Science
Clinical and pathological characteristics of acute myelogenous leukemia in a female koala with diabetes mellitus
Nanao ITOToshinori YOSHIDARho ICHIKAWAEmi MAKINOSatoshi AKEMAJunko FUKUMORINaofumi TAKAHASHIJunta NAKAHARARisako YAMASHITAKai ORIHARAMio KOBAYASHIHou XIANTAOYousuke WATANABESayaka MIZUKAMIMakoto SHIBUTANI
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ジャーナル フリー

2019 年 81 巻 8 号 p. 1229-1233

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A female koala presented with hyperglycemia related to diabetes mellitus diagnosed at 9 years and treated with insulin. She presented with nasal hemorrhage, anemia, leukocytosis, and tachypnea at 10 years. A blood smear examination revealed scattered, atypical large myeloid cells and a clinical diagnosis of myelogenous leukemia was made. White blood cell count reached a maximum of 295 × 102/µl, with evidence of severe regenerative anemia and thrombocytopenia. Grossly, systemic lymph node enlargement, fragile liver with hemorrhage, and bloody ascites were observed. Histopathologically, atypical myeloid cells, including myelocytic and metamyelocytic cells, were scattered in the vasculature and surrounding tissues throughout the organs. The patient was infected with a koala retrovirus, which might have caused the myelogenous leukemia.

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この記事はクリエイティブ・コモンズ [表示 - 非営利 - 改変禁止 4.0 国際]ライセンスの下に提供されています。
https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja
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