2026 Volume 88 Issue 2 Pages 217-221
A six-year-old spayed female domestic shorthair presented with a one-month history of respiratory distress. Echocardiography showed a large lesion adjacent to the left atrium that was compressing the pulmonary vein. Peak pulmonary venous flow velocity was high (1.5 m/sec). The diagnosis was pulmonary vein stenosis due to mass compression. Fine-needle biopsy cytology of the lung mass led to a direct diagnosis of lymphoma. After two weeks of treatment with L-Asparaginase and prednisolone, a reduction in the mass adjacent to the left atrium and slower peak pulmonary venous flow velocity (0.9 m/sec) were observed. Pulmonary vein stenosis was attenuated by a reduction in the size of lymphoma. This is the first case report of secondary pulmonary vein stenosis in a cat.