論文ID: 10-0154
We retrospectively studied the clinical and laboratory features and outcomes of chronic enteropathy in Shiba breed dogs. Among 99 dogs with chronic enteropathy, 21 Shiba dogs (21%) were included in the study (odds ratio, 7.14). No significant differences were seen in signalment, clinical signs, symptoms, or laboratory profiles between Shiba and non-Shiba groups. Severe histopathological lesions in the duodenum were a common finding in the Shiba group. Median overall survival in the Shiba group was 74 days, while median survival duration of dogs in the non-Shiba group could not be determined because more than half of the cases had survived at the end of this study. The difference between groups was statistically significant (P<0.0001). The 6-month and 1-year survival rates for the Shiba group were 46 and 31%, respectively. Conversely, 6-month and 1- and 3-year survival rates for the non-Shiba group were 83, 74 and 67%. The results obtained here demonstrated that the Shiba dog is predisposed to chronic enteropathy, and shows severe duodenum lesions and poor outcomes, indicating a breed-specific disease.
