Journal of Veterinary Medical Science
Online ISSN : 1347-7439
Print ISSN : 0916-7250
ISSN-L : 0916-7250

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Viral-derived DNA invasion and individual variation in an Indonesian population of large flying fox Pteropus vampyrus
Atsuo IIDAHitoshi TAKEMAERonald TARIGANRyosuke KOBAYASHIHirokazu KATOHiroshi SHIMODATsutomu OMATSUSUPRATIKNOChaerul BASRINi Luh Putu Ika MAYASARISrihadi AGUNGPRIYONOKen MAEDATetsuya MIZUTANIEiichi HONDO
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JOURNAL OPEN ACCESS Advance online publication
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Article ID: 21-0115

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Abstract

Here, we performed next-generation sequencing (NGS) on six large flying foxes (Pteropus vampyrus) collected in Indonesia. Seventy-five virus species in the liver tissue of each specimen were listed. Viral homologous sequences in the bat genome were identified from the listed viruses. This finding provides collateral evidence of viral endogenization into the host genome. We found that two of the six specimens bore partial sequences that were homologous to the plant pathogens Geminiviridae and Luteoviridae. These sequences were absent in the P. vampyrus chromosomal sequences. Hence, plant viral homologous sequences were localized to the hepatocytes as extrachromosomal DNA fragments. Therefore, this suggests that the bat is a potential carrier or vector of plant viruses. The present investigation on wild animals offered novel perspectives on viral invasion, variation, and host interaction.

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© 2021 by the Japanese Society of Veterinary Science

This article is licensed under a Creative Commons [Attribution-NonCommercial-NoDerivatives 4.0 International] license.
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