Abstract
Lactate dehydrogenase isoenzyme anomaly was detected in a 5-year-old male mongrel cat with liver disease. The serum LDH zymogram in this case revealed a high percentage of LDH2 and two extra bands close to the anodic and cathodic sides of a missing band of LDH4. These extra bands with abnormal electrophoretic mobility were confirmed by enzyme-immunoelectrophoresis to be originated from a linkage of LDH isoenzyme to IgG.